An endocrine gland is a hormone producing gland such as the ovaries and adrenals.
Your gut bacteria helps produce
  • Estradiol – the protective estrogen
  • 90% of Serotonin production ! Serotonin is one of your happy hormones and its also regulates appetite, sleep, mood and temperature .
Your gut bacteria regulates
  • Melatonin – which regulates our circadian rhythm and sleep cycle
  • Dopamine – all about rewards / addictions
  • Grehlin – your hunger hormone, if your gut bacteria is off you will eat more!
Your gut bacteria
  • Metabolise & excretes bad estrogens
  • Increase stress hormones (adrenaline & nor-adrenaline)
  • Influence your thyroid hormones & thyroid stimulating hormone (TSH)
The gut bacteria regulates estrogens through an enzyme called beta glucaronidase.
This enzyme keeps the ‘bad’ estrogens low in the body and protects you from estrogen dependant cancers.
An alteration in circulating estrogens may contribute to estrogen dominant states.
Estrogen dominant states include
  • Obesity
  • Metabolic syndrome
  • Cancer
  • Endometrial hyperplasia
  • Endometriosis
  • Fibroids
  • Polycystic ovary syndrome
  • Infertility
  • Cardiovascular disease (CVD)
  • Cognitive function decline
Your gut bacteria produce enzymes called the ESTROBOLOME. Your estrobolome controls your estrogen metabolism and excretion.
If your estrobolome is unhealthy, you become estrogen dominant and more prone to the ‘bad’ estrogens affecting your health.
One definition of the Estrobolome is –
“…the aggregate of enteric bacterial genes whose products
are capable of metabolizing estrogens”
“By modulating the enterohepatic circulation of estrogens, the estrobolome affects both the excretion and circulation of estrogens. In turn, the composition of the estrobolome can be shaped by factors such as antibiotics, other drugs, and diet that modulate its functional activity.”

Plottel SC, Blaser MJ.
A healthy Oestrobolome in the gut helps the body excrete estrogen appropriately !
To have happy hormones you need to get your gut right!!
🥑A poor diet, antibiotics, toxins/chemicals, and alcohol worsen your microbiome thus potentially increasing estrogen
🤢Constipation will cause hormone imbalance due to poor excretion of toxins and bad estrogens.
🥦Prebiotics and probiotic supplements and foods are your friend.
🥕A diet rich in plant fibres improves your gut microbiota!
Please reach out if you need guidance with this or other health issues, book a complimentary chat or a consultation online or offline.
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